Zerit®

Fatal lactic acidosis has recently been reported in pregnant women treated throughout gestation with the combination of stavudine (Zerit®) and didanosine (Videx). Lactic acidosis occurs when cells of the body are unable to convert food into usable energy. As a result, excess acid accumulates in the body and vital organs such as the liver or pancreas may be damaged. Severe lactic acidosis is an infrequent, but well-described complication of the class of HIV drugs known as nucleoside analogues. Pancreatitis is also a well-described complication of Videx and Zerit®.

Two treatment-naive patients died of pancreatitis approximately seven months after initiation of treatment with didanosine plus stavudine and protease inhibitor in two clinical trials.

Source: fda.gov

If you or a loved one has been harmed by Zerit®, you may want to contact a Zerit® attorney for more information.